69 MLB Players debut on July 21
| # | Player | debut Date |
|---|---|---|
| 1. | Joe Beckwith | 7/21/1979 |
| 2. | Mike Brown | 7/21/1983 |
| 3. | Mark Brownson | 7/21/1998 |
| 4. | Kit Carson | 7/21/1934 |
| 5. | Harry Colliflower | 7/21/1899 |
| 6. | Dick Colpaert | 7/21/1970 |
| 7. | Brooks Conrad | 7/21/2008 |
| 8. | Larry Crawford | 7/21/1937 |
| 9. | Brad Davis | 7/21/2010 |
| 10. | Abel De Los Santos | 7/21/2015 |
| 11. | Melvin Dorta | 7/21/2006 |
| 12. | Carmen Fanzone | 7/21/1970 |
| 13. | P. J. Forbes | 7/21/1998 |
| 14. | John Frascatore | 7/21/1994 |
| 15. | Mark Gilbert | 7/21/1985 |
| 16. | Zach Green | 7/21/2019 |
| 17. | Pumpsie Green | 7/21/1959 |
| 18. | Don Gross | 7/21/1955 |
| 19. | Tom Hafey | 7/21/1939 |
| 20. | Sam Hairston | 7/21/1951 |
| 21. | Garrett Hampson | 7/21/2018 |
| 22. | Rich Harden | 7/21/2003 |
| 23. | Herb Harris | 7/21/1936 |
| 24. | Vic Harris | 7/21/1972 |
| 25. | J C Hartman | 7/21/1962 |
| 26. | Frank House | 7/21/1950 |
| 27. | Joey Jay | 7/21/1953 |
| 28. | Brian Johnson | 7/21/2015 |
| 29. | Bill Leard | 7/21/1917 |
| 30. | Mark Leonard | 7/21/1990 |
| 31. | Pete LePine | 7/21/1902 |
| 32. | Nook Logan | 7/21/2004 |
| 33. | Bill Long | 7/21/1985 |
| 34. | Pat Lyons | 7/21/1890 |
| 35. | Bobby Madritsch | 7/21/2004 |
| 36. | Jim McAndrew | 7/21/1968 |
| 37. | Darren McCaughan | 7/21/2021 |
| 38. | Tim McKeithan | 7/21/1932 |
| 39. | Conner Menez | 7/21/2019 |
| 40. | Adrian Morejon | 7/21/2019 |
| 41. | Jamie Nelson | 7/21/1983 |
| 42. | Wil Nieves | 7/21/2002 |
| 43. | Aaron Nola | 7/21/2015 |
| 44. | Dave Pickett | 7/21/1898 |
| 45. | Stephen Piscotty | 7/21/2015 |
| 46. | Eric Rasmussen | 7/21/1975 |
| 47. | Bill Reidy | 7/21/1896 |
| 48. | Lenn Sakata | 7/21/1977 |
| 49. | Frank Saucier | 7/21/1951 |
| 50. | Will Sawyer | 7/21/1883 |
| 51. | Skeeter Scalzi | 7/21/1939 |
| 52. | Marco Scutaro | 7/21/2002 |
| 53. | Jae Weong Seo | 7/21/2002 |
| 54. | Sibby Sisti | 7/21/1939 |
| 55. | Grady Sizemore | 7/21/2004 |
| 56. | Anthony Slama | 7/21/2010 |
| 57. | Steve Slayton | 7/21/1928 |
| 58. | Milt Smith | 7/21/1955 |
| 59. | Harry Smythe | 7/21/1929 |
| 60. | Mario Soto | 7/21/1977 |
| 61. | Craig Tatum | 7/21/2009 |
| 62. | Bill Tobin | 7/21/1880 |
| 63. | Jake Virtue | 7/21/1890 |
| 64. | Justin Williams | 7/21/2018 |
| 65. | Oscar Woehrlin | 7/21/1895 |
| 66. | Doc Wood | 7/21/1923 |
| 67. | David Wright | 7/21/2004 |
| 68. | Kip Young | 7/21/1978 |
| 69. | Jeff Zaske | 7/21/1984 |
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