Top 30 Lifetime MLB DD (Diametric Differential) leaders
*5000 career AB minimum
| Rank | Name | HR | SO | DD = 4 x HR - SO | DD = HRBASES - SO | DD |
|---|---|---|---|---|---|---|
| 1 | Hank Aaron | 755 | 1383 | 4 x 755 - 1383 | 3020 - 1383 | 1637 |
| 2 | Babe Ruth | 714 | 1330 | 4 x 714 - 1330 | 2856 - 1330 | 1526 |
| 3 | Barry Bonds | 762 | 1539 | 4 x 762 - 1539 | 3048 - 1539 | 1509 |
| 4 | Albert Pujols | 703 | 1404 | 4 x 703 - 1404 | 2812 - 1404 | 1408 |
| 5 | Ted Williams | 521 | 709 | 4 x 521 - 709 | 2084 - 709 | 1375 |
| 6 | Stan Musial | 475 | 696 | 4 x 475 - 696 | 1900 - 696 | 1204 |
| 7 | Lou Gehrig | 493 | 790 | 4 x 493 - 790 | 1972 - 790 | 1182 |
| 8 | Mel Ott | 511 | 896 | 4 x 511 - 896 | 2044 - 896 | 1148 |
| 9 | Willie Mays | 660 | 1526 | 4 x 660 - 1526 | 2640 - 1526 | 1114 |
| 10 | Joe DiMaggio | 361 | 369 | 4 x 361 - 369 | 1444 - 369 | 1075 |
| 11 | Yogi Berra | 358 | 414 | 4 x 358 - 414 | 1432 - 414 | 1018 |
| 12 | Rafael Palmeiro | 569 | 1348 | 4 x 569 - 1348 | 2276 - 1348 | 928 |
| 13 | Johnny Mize | 359 | 524 | 4 x 359 - 524 | 1436 - 524 | 912 |
| 14 | Gary Sheffield | 509 | 1171 | 4 x 509 - 1171 | 2036 - 1171 | 865 |
| 15 | Jimmie Foxx | 534 | 1311 | 4 x 534 - 1311 | 2136 - 1311 | 825 |
| 16 | Ernie Banks | 512 | 1236 | 4 x 512 - 1236 | 2048 - 1236 | 812 |
| 17 | Frank Robinson | 586 | 1532 | 4 x 586 - 1532 | 2344 - 1532 | 812 |
| 18 | Vladimir Guerrero | 449 | 985 | 4 x 449 - 985 | 1796 - 985 | 811 |
| 19 | Ted Kluszewski | 279 | 365 | 4 x 279 - 365 | 1116 - 365 | 751 |
| 20 | Ken Griffey | 630 | 1779 | 4 x 630 - 1779 | 2520 - 1779 | 741 |
| 21 | Mark McGwire | 583 | 1596 | 4 x 583 - 1596 | 2332 - 1596 | 736 |
| 22 | Ralph Kiner | 369 | 749 | 4 x 369 - 749 | 1476 - 749 | 727 |
| 23 | Frank Thomas | 521 | 1397 | 4 x 521 - 1397 | 2084 - 1397 | 687 |
| 24 | Chuck Klein | 300 | 521 | 4 x 300 - 521 | 1200 - 521 | 679 |
| 25 | Billy Williams | 426 | 1046 | 4 x 426 - 1046 | 1704 - 1046 | 658 |
| 26 | Rocky Colavito | 374 | 880 | 4 x 374 - 880 | 1496 - 880 | 616 |
| 27 | Mike Piazza | 427 | 1113 | 4 x 427 - 1113 | 1708 - 1113 | 595 |
| 28 | Harmon Killebrew | 573 | 1699 | 4 x 573 - 1699 | 2292 - 1699 | 593 |
| 29 | Al Kaline | 399 | 1020 | 4 x 399 - 1020 | 1596 - 1020 | 576 |
| 30 | Albert Belle | 381 | 961 | 4 x 381 - 961 | 1524 - 961 | 563 |
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