68 MLB Players debut on May 12
| # | Player | debut Date |
|---|---|---|
| 1. | Dave Adlesh | 5/12/1963 |
| 2. | John Ake | 5/12/1884 |
| 3. | Cam Alldred | 5/12/2022 |
| 4. | Alex Arias | 5/12/1992 |
| 5. | Rylan Bannon | 5/12/2022 |
| 6. | Bob Beall | 5/12/1975 |
| 7. | Anthony Bemboom | 5/12/2019 |
| 8. | Dennis Bennett | 5/12/1962 |
| 9. | Bill Bevens | 5/12/1944 |
| 10. | Jim Brady | 5/12/1956 |
| 11. | Jimmy Callahan | 5/12/1894 |
| 12. | Chris Carpenter | 5/12/1997 |
| 13. | Bill Caudill | 5/12/1979 |
| 14. | Wilson Collins | 5/12/1913 |
| 15. | Tom Connolly | 5/12/1915 |
| 16. | Jose De La Torre | 5/12/2013 |
| 17. | John Deering | 5/12/1903 |
| 18. | Cy Ferry | 5/12/1904 |
| 19. | Jeff Fiorentino | 5/12/2005 |
| 20. | Giovanny Gallegos | 5/12/2017 |
| 21. | Edgar Gonzalez | 5/12/2008 |
| 22. | Frank Grube | 5/12/1931 |
| 23. | Cole Hamels | 5/12/2006 |
| 24. | Ed Hanyzewski | 5/12/1942 |
| 25. | Ubaldo Heredia | 5/12/1987 |
| 26. | David Hess | 5/12/2018 |
| 27. | Cole Irvin | 5/12/2019 |
| 28. | Marty Janzen | 5/12/1996 |
| 29. | Bob Katz | 5/12/1944 |
| 30. | Brandon Kolb | 5/12/2000 |
| 31. | Paul Krichell | 5/12/1911 |
| 32. | Mickey Lolich | 5/12/1963 |
| 33. | Hector Lopez | 5/12/1955 |
| 34. | Jose Macias | 5/12/1999 |
| 35. | Parker Markel | 5/12/2019 |
| 36. | Corbin Martin | 5/12/2019 |
| 37. | Doug Mathis | 5/12/2008 |
| 38. | Kevin Mattison | 5/12/2012 |
| 39. | Bill McAfee | 5/12/1930 |
| 40. | Algie McBride | 5/12/1896 |
| 41. | Edgar McNabb | 5/12/1893 |
| 42. | Ralph Milliard | 5/12/1996 |
| 43. | Agustin Montero | 5/12/2006 |
| 44. | Tom Needham | 5/12/1904 |
| 45. | Eury Perez | 5/12/2023 |
| 46. | Ray Pierce | 5/12/1924 |
| 47. | Andy Piercy | 5/12/1881 |
| 48. | Gaylen Pitts | 5/12/1974 |
| 49. | Eric Plunk | 5/12/1986 |
| 50. | Cody Poteet | 5/12/2021 |
| 51. | Jeff Reboulet | 5/12/1992 |
| 52. | Chris Roberson | 5/12/2006 |
| 53. | George Rooks | 5/12/1891 |
| 54. | Amauri Sanit | 5/12/2011 |
| 55. | Dan Schneider | 5/12/1963 |
| 56. | Todd Self | 5/12/2005 |
| 57. | Wascar Serrano | 5/12/2001 |
| 58. | Zak Shinall | 5/12/1993 |
| 59. | Dale Sveum | 5/12/1986 |
| 60. | Noah Syndergaard | 5/12/2015 |
| 61. | Bud Teachout | 5/12/1930 |
| 62. | Frank Tepedino | 5/12/1967 |
| 63. | Harry Wilke | 5/12/1927 |
| 64. | Roy Wise | 5/12/1944 |
| 65. | Blake Wood | 5/12/2010 |
| 66. | Archie Yelle | 5/12/1917 |
| 67. | Ed Yewell | 5/12/1884 |
| 68. | Jason Young | 5/12/2003 |
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