76 MLB Players debut on May 15
| # | Player | debut Date |
|---|---|---|
| 1. | David Adams | 5/15/2013 |
| 2. | Jesus Aguilar | 5/15/2014 |
| 3. | Chuck Aleno | 5/15/1941 |
| 4. | Shaun Anderson | 5/15/2019 |
| 5. | Jake Aydelott | 5/15/1884 |
| 6. | Cliff Bartosh | 5/15/2004 |
| 7. | George Beck | 5/15/1914 |
| 8. | Erik Bennett | 5/15/1995 |
| 9. | Tom Borland | 5/15/1960 |
| 10. | Cody Bradford | 5/15/2023 |
| 11. | Don Buschhorn | 5/15/1965 |
| 12. | Sal Campfield | 5/15/1896 |
| 13. | Roger Clemens | 5/15/1984 |
| 14. | Clem Clemens | 5/15/1914 |
| 15. | Ed Coughlin | 5/15/1884 |
| 16. | Jacob deGrom | 5/15/2014 |
| 17. | Jake Diekman | 5/15/2012 |
| 18. | Jack DiLauro | 5/15/1969 |
| 19. | Scott Dohmann | 5/15/2004 |
| 20. | Jim Egan | 5/15/1882 |
| 21. | Johnny Estrada | 5/15/2001 |
| 22. | Roy Evans | 5/15/1897 |
| 23. | Pete Filson | 5/15/1982 |
| 24. | Frank Foreman | 5/15/1884 |
| 25. | Tony Fossas | 5/15/1988 |
| 26. | Ryan Franklin | 5/15/1999 |
| 27. | Luke French | 5/15/2009 |
| 28. | Jerry Goff | 5/15/1990 |
| 29. | Ted Gray | 5/15/1946 |
| 30. | Nick Green | 5/15/2004 |
| 31. | Michael Grove | 5/15/2022 |
| 32. | Javy Guerra | 5/15/2011 |
| 33. | Jake Hager | 5/15/2021 |
| 34. | Bill Harbridge | 5/15/1875 |
| 35. | Claude Hendrix | 5/15/1911 |
| 36. | Elian Herrera | 5/15/2012 |
| 37. | Alex Hinshaw | 5/15/2008 |
| 38. | Colin Holderman | 5/15/2022 |
| 39. | Byron Houck | 5/15/1912 |
| 40. | Dan Howley | 5/15/1913 |
| 41. | Garey Ingram | 5/15/1994 |
| 42. | Garrett Jones | 5/15/2007 |
| 43. | Eric King | 5/15/1986 |
| 44. | Jake Knodell | 5/15/1874 |
| 45. | Cliff Lee | 5/15/1919 |
| 46. | Jon Lieber | 5/15/1994 |
| 47. | Jesse Litsch | 5/15/2007 |
| 48. | Lyle Luttrell | 5/15/1956 |
| 49. | Danny Mahoney | 5/15/1911 |
| 50. | Jim Manning | 5/15/1884 |
| 51. | Brett Marshall | 5/15/2013 |
| 52. | Allen McDill | 5/15/1997 |
| 53. | Matt McLain | 5/15/2023 |
| 54. | Sam Moffet | 5/15/1884 |
| 55. | Pat Moran | 5/15/1901 |
| 56. | Chris Nichting | 5/15/1995 |
| 57. | Gene Ratliff | 5/15/1965 |
| 58. | Pete Redfern | 5/15/1976 |
| 59. | Austin Riley | 5/15/2019 |
| 60. | Steve Scarsone | 5/15/1992 |
| 61. | Barney Schreiber | 5/15/1911 |
| 62. | Hank Severeid | 5/15/1911 |
| 63. | Jon Shave | 5/15/1993 |
| 64. | Bryan Stephens | 5/15/1947 |
| 65. | Paul Strand | 5/15/1913 |
| 66. | Sullivan | 5/15/1875 |
| 67. | Tom Sullivan | 5/15/1922 |
| 68. | Pedro Valdes | 5/15/1996 |
| 69. | Jared Walsh | 5/15/2019 |
| 70. | Bill Webb | 5/15/1943 |
| 71. | Ted Welch | 5/15/1914 |
| 72. | Todd Wellemeyer | 5/15/2003 |
| 73. | Casper Wells | 5/15/2010 |
| 74. | Chase Whitley | 5/15/2014 |
| 75. | Grady Wilson | 5/15/1948 |
| 76. | Kevin Youkilis | 5/15/2004 |
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