189 MLB Players debut on September 12
| # | Player | debut Date |
|---|---|---|
| 1. | Jim Adduci | 9/12/1983 |
| 2. | Steve Adkins | 9/12/1990 |
| 3. | Gary Alexander | 9/12/1975 |
| 4. | Jorge Alfaro | 9/12/2016 |
| 5. | Sherten Apostel | 9/12/2020 |
| 6. | Victor Arano | 9/12/2017 |
| 7. | Dave Baker | 9/12/1982 |
| 8. | Junie Barnes | 9/12/1934 |
| 9. | Robbie Beckett | 9/12/1996 |
| 10. | Ronnie Belliard | 9/12/1998 |
| 11. | Buddy Biancalana | 9/12/1982 |
| 12. | Joe Birmingham | 9/12/1906 |
| 13. | Mark Bomback | 9/12/1978 |
| 14. | Bobby Bonner | 9/12/1980 |
| 15. | Emmett Bowles | 9/12/1922 |
| 16. | Kevin Brown | 9/12/1996 |
| 17. | Earl Browne | 9/12/1935 |
| 18. | Billy Bryan | 9/12/1961 |
| 19. | Sandy Burk | 9/12/1910 |
| 20. | Willie Calhoun | 9/12/2017 |
| 21. | Ray Callahan | 9/12/1915 |
| 22. | Bruce Campbell | 9/12/1930 |
| 23. | Jose Capellan | 9/12/2004 |
| 24. | Doug Capilla | 9/12/1976 |
| 25. | Albin Carlstrom | 9/12/1911 |
| 26. | Dixie Carroll | 9/12/1919 |
| 27. | Sean Casey | 9/12/1997 |
| 28. | Charlie Chant | 9/12/1975 |
| 29. | Italo Chelini | 9/12/1935 |
| 30. | Don Choate | 9/12/1960 |
| 31. | Jack Clark | 9/12/1975 |
| 32. | Frank Colman | 9/12/1942 |
| 33. | Merl Combs | 9/12/1947 |
| 34. | Earl Cook | 9/12/1941 |
| 35. | Dennis Cook | 9/12/1988 |
| 36. | Joe Crede | 9/12/2000 |
| 37. | Jim Crowell | 9/12/1997 |
| 38. | Bill Cunningham | 9/12/1910 |
| 39. | Walter Curley | 9/12/1899 |
| 40. | John Curran | 9/12/1876 |
| 41. | Paul Dade | 9/12/1975 |
| 42. | Pat Darcy | 9/12/1974 |
| 43. | Mark Davis | 9/12/1980 |
| 44. | Hank DeBerry | 9/12/1916 |
| 45. | John Denny | 9/12/1974 |
| 46. | Ducky Detweiler | 9/12/1942 |
| 47. | Mario Diaz | 9/12/1987 |
| 48. | Elias Diaz | 9/12/2015 |
| 49. | Buzz Dozier | 9/12/1947 |
| 50. | Hunter Dozier | 9/12/2016 |
| 51. | Tim Drummond | 9/12/1987 |
| 52. | Joe Dunn | 9/12/1908 |
| 53. | Justin Dunn | 9/12/2019 |
| 54. | George Durning | 9/12/1925 |
| 55. | Rawly Eastwick | 9/12/1974 |
| 56. | Vallie Eaves | 9/12/1935 |
| 57. | Robert Ellis | 9/12/1996 |
| 58. | Bill Essick | 9/12/1906 |
| 59. | Joe Ferguson | 9/12/1970 |
| 60. | Frank Fernandez | 9/12/1967 |
| 61. | Bob Ferris | 9/12/1979 |
| 62. | Lou Finney | 9/12/1931 |
| 63. | Rube Fischer | 9/12/1941 |
| 64. | Tom Fletcher | 9/12/1962 |
| 65. | Kevin Foster | 9/12/1993 |
| 66. | Jim French | 9/12/1965 |
| 67. | Bill Fulton | 9/12/1987 |
| 68. | Joe Gates | 9/12/1978 |
| 69. | John Gaub | 9/12/2011 |
| 70. | Brian Giles | 9/12/1981 |
| 71. | Jonny Gomes | 9/12/2003 |
| 72. | Harvey Green | 9/12/1935 |
| 73. | Lee Guetterman | 9/12/1984 |
| 74. | Harry Gumbert | 9/12/1935 |
| 75. | Bucky Guth | 9/12/1972 |
| 76. | Albert Hall | 9/12/1981 |
| 77. | Bob Hamelin | 9/12/1993 |
| 78. | Ike Hampton | 9/12/1974 |
| 79. | Tim Harkness | 9/12/1961 |
| 80. | Terry Harper | 9/12/1980 |
| 81. | Jeff Hartsock | 9/12/1992 |
| 82. | Bob Heise | 9/12/1967 |
| 83. | Evelio Hernandez | 9/12/1956 |
| 84. | Art Herring | 9/12/1929 |
| 85. | Eli Hodkey | 9/12/1946 |
| 86. | Mike Howard | 9/12/1981 |
| 87. | John Hummel | 9/12/1905 |
| 88. | Ron Jackson | 9/12/1975 |
| 89. | Ken Jackson | 9/12/1987 |
| 90. | Damian Jackson | 9/12/1996 |
| 91. | Skip James | 9/12/1977 |
| 92. | Daulton Jefferies | 9/12/2020 |
| 93. | Miguel Jimenez | 9/12/1993 |
| 94. | Ron Johnson | 9/12/1982 |
| 95. | Chet Johnson | 9/12/1946 |
| 96. | Jack Kading | 9/12/1910 |
| 97. | Ray Keating | 9/12/1912 |
| 98. | Fred Ketchum | 9/12/1899 |
| 99. | Wayne Kirby | 9/12/1991 |
| 100. | Alejandro Kirk | 9/12/2020 |
| 101. | Ryan Klesko | 9/12/1992 |
| 102. | Dave Koslo | 9/12/1941 |
| 103. | Tom Kramer | 9/12/1991 |
| 104. | Howie Krist | 9/12/1937 |
| 105. | Walt Lanfranconi | 9/12/1941 |
| 106. | Andy Lapihuska | 9/12/1942 |
| 107. | Charlie Lau | 9/12/1956 |
| 108. | Rudy Law | 9/12/1978 |
| 109. | Leonard | 9/12/1892 |
| 110. | Jim Lewis | 9/12/1979 |
| 111. | Mark Little | 9/12/1998 |
| 112. | Jimmie Long | 9/12/1922 |
| 113. | Art Lopatka | 9/12/1945 |
| 114. | Lefty Lorenzen | 9/12/1913 |
| 115. | Mike Lum | 9/12/1967 |
| 116. | Trey Lunsford | 9/12/2002 |
| 117. | Tony Lupien | 9/12/1940 |
| 118. | Charlie Luskey | 9/12/1901 |
| 119. | Edgar Martinez | 9/12/1987 |
| 120. | Hank Mason | 9/12/1958 |
| 121. | Bert Maxwell | 9/12/1906 |
| 122. | George McBride | 9/12/1901 |
| 123. | Terry McDermott | 9/12/1972 |
| 124. | Howard McGraner | 9/12/1912 |
| 125. | Deck McGuire | 9/12/2017 |
| 126. | Lennie Merullo | 9/12/1941 |
| 127. | Randy Milligan | 9/12/1987 |
| 128. | Nate Minchey | 9/12/1993 |
| 129. | Paul Minner | 9/12/1946 |
| 130. | Dave Mlicki | 9/12/1992 |
| 131. | Sid Monge | 9/12/1975 |
| 132. | Dee Moore | 9/12/1936 |
| 133. | Jovani Moran | 9/12/2021 |
| 134. | Gabriel Moya | 9/12/2017 |
| 135. | Tom Murphy | 9/12/2015 |
| 136. | Greg Myers | 9/12/1987 |
| 137. | Josh Newman | 9/12/2007 |
| 138. | Merlin Nippert | 9/12/1962 |
| 139. | Renato Nunez | 9/12/2016 |
| 140. | Randy O'Neal | 9/12/1984 |
| 141. | Mickey O'Neil | 9/12/1919 |
| 142. | Jim Obradovich | 9/12/1978 |
| 143. | Al Olmsted | 9/12/1980 |
| 144. | Matt Olson | 9/12/2016 |
| 145. | Tom Paciorek | 9/12/1970 |
| 146. | Pat Perry | 9/12/1985 |
| 147. | Cap Peterson | 9/12/1962 |
| 148. | Calvin Pickering | 9/12/1998 |
| 149. | Arquimedez Pozo | 9/12/1995 |
| 150. | Johan Quezada | 9/12/2020 |
| 151. | Ryan Raburn | 9/12/2004 |
| 152. | Jody Reed | 9/12/1987 |
| 153. | Ray Roberts | 9/12/1919 |
| 154. | Esmil Rogers | 9/12/2009 |
| 155. | John Romano | 9/12/1958 |
| 156. | Mark Ross | 9/12/1982 |
| 157. | Jim Russell | 9/12/1942 |
| 158. | Clint Sammons | 9/12/2007 |
| 159. | Bob Saverine | 9/12/1959 |
| 160. | Mike Schmidt | 9/12/1972 |
| 161. | Paddy Siglin | 9/12/1914 |
| 162. | Dan Smith | 9/12/1992 |
| 163. | Pavin Smith | 9/12/2020 |
| 164. | Jeff Sparks | 9/12/1999 |
| 165. | Tris Speaker | 9/12/1907 |
| 166. | Roy Staiger | 9/12/1975 |
| 167. | Buck Stanley | 9/12/1911 |
| 168. | Dolly Stark | 9/12/1909 |
| 169. | Elmer Steele | 9/12/1907 |
| 170. | Terry Steinbach | 9/12/1986 |
| 171. | DJ Stewart | 9/12/2018 |
| 172. | Mike Strahler | 9/12/1970 |
| 173. | Augie Swentor | 9/12/1922 |
| 174. | Lee Tate | 9/12/1958 |
| 175. | Fred Taylor | 9/12/1950 |
| 176. | Tom Thobe | 9/12/1995 |
| 177. | Erick Threets | 9/12/2007 |
| 178. | Jorge Toca | 9/12/1999 |
| 179. | Angel Torres | 9/12/1977 |
| 180. | Robin Ventura | 9/12/1989 |
| 181. | Dan Vogelbach | 9/12/2016 |
| 182. | Terrell Wade | 9/12/1995 |
| 183. | Art Warren | 9/12/2019 |
| 184. | Matt Watson | 9/12/2003 |
| 185. | Ernie Whitt | 9/12/1976 |
| 186. | Don Williams | 9/12/1958 |
| 187. | Jeff Williams | 9/12/1999 |
| 188. | Jack Wisner | 9/12/1919 |
| 189. | James York | 9/12/1919 |
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